The CURLY study is trying to find the best way to help children with a urine or wee infection.

Urine infections are very common in children and happen when germs get into their body and make them poorly.

It can cause high temperatures, tummy pains and sickness.

We can usually stop the infection using an antibiotic called cefalexin.

Cefalexin is very safe and is used to treat most urine infections.

Side effects are minor and rare but, in general, it is better to take antibiotics for as little time as possible.

In adults we can usually stop the infection in just a few days.

Doctors are not sure if this is the same for children.

The CURLY study will find out for how long the medicine should be given to children to make them better.

We will compare medicine taken for 3, 5, 6, 8 and 10 days.

The number of days each child takes the medicine will be decided by chance, using a process called randomisation.

All children in the study will be checked to make sure the infection goes away.

We are asking lots of children with a urine infection if they want to take part.

If you decide to take part, we will ask parents to sign a consent form and older children to sign an assent form.

We will ask children and parents to fill in a questionnaire to tell us about how the infection is affecting life.

We will show families how to use an app to keep track of the amount of medicine taken and any symptoms that develop.

We will then give you the medicine to start taking at home.

After 2 weeks you will have an appointment to check the infection has cleared.

We will again ask you to fill in a questionnaire and collect some wee in a pot.

After 30 days you will fill in another questionnaire at home and provide another wee sample that you post back to us.

At the end of the study we will offer you a £20 gift voucher to thank you.

By taking part in the CURLY study you will help us know the best way to treat children with a urine infection in the future.

The doctors and nurses will be happy to answer any questions.